How the Peptiblox Score works
Every peptide in our library gets three ratings: how strong the human evidence is,where it stands with the FDA, and how you can legitimately access it. The score describes the evidence. It is never a recommendation to use anything.
Key facts
- Evidence is graded A to D based on published human research, not on marketing or anecdotes.
- FDA status comes from FDA documents and advisory committee votes, dated on each profile.
- Every profile lists the sources behind its grade.
- Scores were last reviewed on October 1, 2026 and are updated when new trials or FDA actions land.
- Today: 2 peptides graded A, 3 peptides graded B, 6 peptides graded C, 5 peptides graded D.
1. Evidence grade
FDA-approved for its main use, backed by multiple large randomized controlled trials in humans.
At least one solid controlled human trial with meaningful outcomes, or approved only for a narrow use while people discuss it for others.
Small, early or uncontrolled human studies. Promising signals, not proof.
Mostly animal or lab research, with little or no published human evidence.
2. FDA status
- FDA-approved: An FDA-approved medicine, available by prescription.
- In FDA trials: In formal FDA clinical trials; not yet approved or sold.
- PCAC recommended: FDA's compounding advisory committee voted to recommend it for the 503A Bulks List. The FDA still has to finish rulemaking.
- Compoundable: Licensed compounding pharmacies can currently prepare it with a prescription.
- Awaiting FDA review: Off the FDA restricted list, but not yet reviewed for the compounding Bulks List.
- Not recommended: Reviewed by the FDA advisory committee and not recommended for compounding.
- Restricted: Flagged by the FDA over safety concerns; compounding is restricted.
For the full timeline of FDA decisions, see the legal status tracker.
3. Legitimate access
We only describe legal routes: a brand-name prescription, a prescription filled by a licensed compounding pharmacy, or a clinical trial. When there is no clear legal route yet, we say so. We never link to sellers of "research chemicals."
What the score is not
It is not medical advice, a ranking of what works best for you, or an endorsement. Two peptides with the same grade can be right for very different people, or for no one. That is a conversation for a licensed provider, which is why every profile lets you add a peptide to yourstack and bring the list to your appointment.