Recovery

BPC-157

Body Protection Compound 157

BPC-157 is a 15-amino-acid synthetic peptide derived from a protein found in gastric juice. It is widely discussed for injury recovery, but it is not an FDA-approved drug and its human research is very limited.

Key facts

  • Commonly discussed for: tendon, ligament and gut healing.
  • Evidence (D): A 2025 systematic review found 35 preclinical studies and just 1 clinical study (a retrospective chart review of knee pain in 16 patients); the only other human report is a 2-person IV safety pilot. No randomized controlled human trial has been published.
  • FDA status: PCAC recommended. FDA moved BPC-157 off its Category 2 restricted list in April 2026, and on July 23, 2026 the PCAC voted 8-6 (1 abstention) to recommend it for the 503A Bulks List for ulcerative colitis; FDA must still publish a proposed rule; none appeared in the Federal Register as of October 1, 2026.
  • Legitimate access: No clear legal route yet.
  • Last reviewed: October 1, 2026.

Read the deep dives

Thinking about BPC-157?

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Sources