Skin
GHK-Cu
Copper tripeptide-1
GHK-Cu is a naturally occurring copper-binding peptide found in human plasma, used for years as a cosmetic skincare ingredient. Injectable use is a separate question, and FDA has not yet decided whether pharmacies may compound it.
Key facts
- Commonly discussed for: skin quality, wound healing and hair.
- Evidence (C): Human data are small topical studies, such as a randomized trial in which 13 laser-resurfacing patients completed follow-up and blinded raters found no difference in redness or wrinkles; most wound-healing data are from animals. FDA notes limited human data for injectable use.
- FDA status: Awaiting FDA review. Injectable GHK-Cu was removed from FDA's Category 2 list in April 2026 but is not on the 503A Bulks List; the PCAC is scheduled to review it at a meeting before the end of February 2027.
- Legitimate access: No clear legal route yet.
- Last reviewed: October 1, 2026.
Thinking about GHK-Cu?
Add it to your stack, then bring the list to a licensed provider. They can tell you whether it fits your health picture and what the legitimate options are. Peptiblox never sells peptides or links to sellers. Check the legal status tracker for the latest FDA changes.
Open my stack →Sources
- Pickart et al. GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration. Biomed Res Int, 2015
- Miller et al. Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin. Arch Facial Plast Surg, 2006
- FDA: Certain bulk drug substances for use in compounding that may present significant safety risks (Category 2 list)
- FDA: Meeting of the Pharmacy Compounding Advisory Committee (upcoming 2027 meeting)